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POMC Polyclonal Antibody

Product Specifications

Background

Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH, α- and β-MSH, β-and γ-LPH, CLIP, β-endorphin, and N-POMC. POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety. POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat.

Abbreviation

POMC

UniProt

P01189

Host

Rabbit

Reactivity

Mouse; Rat

Immunogen

Synthetic peptide.

Target

Pro-opiomelanocortin; Corticotropin-lipotropin; NPP; Melanotropin gamma; Gamma-MSH; Potential peptide; Corticotropin; ACTH; CLIP; Alpha-MSH; Beta-LPH; Gamma-LPH; Beta-MSH; Beta-endorphin; Met-enkephalin

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Metabolism; Neuroscience; Signal Transduction

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:1000-1:2000

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

29 kDa

Observed Molecular Weight

35 kDa, 16 kDa

Isotype

IgG

Available Sizes

Curated Selection

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