Serpin A1 Polyclonal Antibody
Product Specifications
Background
Serpin A1 is the archetypal member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in the liver and secreted into the bloodstream with the major function to protect tissues against neutrophil elastase.A severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatitis, cirrhosis, and hepatocellular carcinoma.
Abbreviation
Serpin A1
UniProt
P17475
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Rat Serpin A1 protein expressed by E.coli
Target
Alpha 1 Antitrypsin; Serpina1; Alpha-1-antiproteinase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:100-1:200; IHC 1:2000-1:4000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa
Observed Molecular Weight
60kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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