PON3/paraoxonase 3 Polyclonal Antibody
Product Specifications
Background
The paraoxonase (PON) gene family of antioxidant enzymes includes three known members located adjacent to each other on chromosome 7. Paraoxonase/lactonase 3 (PON3) is a 354 amino acid, 39.6 kDa protein that is secreted into the bloodstream and associates with high-density lipoprotein (HDL) . PON3 has lactonase activity (EC 3.1.1) and rapidly hydrolyzes lactones. PON3 exhibits no paraoxonase and very limited arylesterase activities. PON3 is an important antioxidant and can inhibit the oxidation of low-density lipoprotein (LDL), a function that may slow the initiation and progression of atherosclerosis.
Abbreviation
PON3
UniProt
Q15166
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
Recombinant Human PON3 protein expressed by E.coli.
Target
Serum paraoxonase/lactonase 3; PON3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Cardiovascular; Signal Transduction; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
39kDa
Observed Molecular Weight
40kDa
Isotype
IgG
Available Sizes
Documents
Curated Selection
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