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PCNA Polyclonal Antibody

Product Specifications

Background

This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Abbreviation

PCNA

UniProt

P12004

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human Proliferating cell nuclear antigen protein

Target

ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNAR; Polymerase delta accessory protein

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell markers; Cancer; Isotype/Loading Controls

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

28 kDa

Observed Molecular Weight

34 lDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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