PCNA Polyclonal Antibody
Product Specifications
Background
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Abbreviation
PCNA
UniProt
P12004
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Proliferating cell nuclear antigen protein
Target
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNAR; Polymerase delta accessory protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell markers; Cancer; Isotype/Loading Controls
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Observed Molecular Weight
34 lDa
Isotype
IgG
Available Sizes
Documents
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