FGB Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Abbreviation
FGB
UniProt
P14480
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Rat Fibrinogen beta chain protein
Target
Beta fibrinogen; Epididymis Secretory Sperm Binding Protein Li 78p; FGB; Fibrinogen beta chain; HEL-S-78p
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cardiovascular; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:2000-1:4000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
55 kDa
Isotype
IgG
Available Sizes
Documents
Frequently Asked Questions
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