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Chromogranin A Polyclonal Antibody

Product Specifications

Background

Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine) . CgA is one of the most used tumor markers in NET's (neuroendocrine tumors), and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.

Abbreviation

Chromogranin A

UniProt

P26339

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant Mouse Chromogranin-A protein

Target

Beta Granin; betagranin (N-terminal fragment of chromogranin A) ; catestatin; CgA; CHG A; Chga; chromofungin; Chromogranin A; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; CMGA; ER-37; Pancreastatin; Parastatin; Parathyroid secretory protein 1; Pituitary secretory protein I; Secretory protein I; SP I; SP-I; SP1; SPI; Vasostatin; Vasostatin I; Vasostatin II

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Neuroscience; Signal Transduction; Tags and Cell Markers

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:100-1:300

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

51 kDa

Observed Molecular Weight

51 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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