YAP1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Abbreviation
YAP
UniProt
P46937
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human YAP
Target
65 kDa Yes associated protein;65 kDa Yes-associated protein; COB1; YAp 1; YAP 65; YAP; YAP1; YAP1; YAP2; YAP65; yes -associated protein delta; Yes associated protein 1 65kDa; Yes associated protein 1; Yes associated protein 2; yes associated protein beta; YKI; Yorkie homolog
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
49kDa
Observed Molecular Weight
67kDa
Isotype
IgG
Available Sizes
Curated Selection
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