TGF β Receptor II Polyclonal Antibody

Product Specifications

Background

TGFBR2 (Transforming Growth Factor BetaReceptor2) is a Protein Coding gene. Diseases associated withTGFBR2 includeLoeys-Dietz Syndrome 2andEsophageal Cancer. Among its related pathways areSMAD2/3 MH2 Domain Mutants in CancerandExtracellular vesicle-mediated signaling in recipient cells. GO annotations related to this gene includetransferase activity, transferring phosphorus-containing groupsandprotein tyrosine kinase activity. An important paralog of this gene isACVR2B.

Abbreviation

TGFβ RII

UniProt

P37173

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from the Internal region of human TGFβ RII

Target

AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TbetaR II; TbetaR-II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta receptor type IIB; TGF beta type II receptor; TGF-beta receptor type II; TGF-beta receptor type-2; TGF-beta type II receptor; TGF-beta-R2; TGFB R2; TGFbeta - RII; TGFbeta RII; Tgfbr2; TGFR-2; TGFR2; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II; Transforming growth factor beta receptor type IIC; Transforming growth factor; beta receptor II (70/80kDa) ; transforming growth factor; beta receptor II alpha; transforming growth factor; beta receptor II beta; transforming growth factor; beta receptor II delta; transforming growth factor; beta receptor II epsilon; transforming growth factor; beta receptor II gamma; Transforming growth factor-beta receptor type II

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC-p

Field of Research

Cancer; Signal Transduction; Stem Cells

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:100-1:300

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

65kDa

Observed Molecular Weight

65kDa

Citation 01

https://www.nature.com/articles/s41467-022-35262-w

Citation 02

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006815/

Isotype

IgG

Available Sizes

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