TGF β Receptor II Polyclonal Antibody
Product Specifications
Background
TGFBR2 (Transforming Growth Factor BetaReceptor2) is a Protein Coding gene. Diseases associated withTGFBR2 includeLoeys-Dietz Syndrome 2andEsophageal Cancer. Among its related pathways areSMAD2/3 MH2 Domain Mutants in CancerandExtracellular vesicle-mediated signaling in recipient cells. GO annotations related to this gene includetransferase activity, transferring phosphorus-containing groupsandprotein tyrosine kinase activity. An important paralog of this gene isACVR2B.
Abbreviation
TGFβ RII
UniProt
P37173
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human TGFβ RII
Target
AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TbetaR II; TbetaR-II; TGF beta receptor type 2; TGF beta receptor type II; TGF beta receptor type IIB; TGF beta type II receptor; TGF-beta receptor type II; TGF-beta receptor type-2; TGF-beta type II receptor; TGF-beta-R2; TGFB R2; TGFbeta - RII; TGFbeta RII; Tgfbr2; TGFR-2; TGFR2; Transforming growth factor beta receptor II; Transforming growth factor beta receptor type II; Transforming growth factor beta receptor type IIC; Transforming growth factor; beta receptor II (70/80kDa) ; transforming growth factor; beta receptor II alpha; transforming growth factor; beta receptor II beta; transforming growth factor; beta receptor II delta; transforming growth factor; beta receptor II epsilon; transforming growth factor; beta receptor II gamma; Transforming growth factor-beta receptor type II
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
65kDa
Observed Molecular Weight
65kDa
Citation 01
https://www.nature.com/articles/s41467-022-35262-w
Citation 02
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006815/
Isotype
IgG
Available Sizes
Curated Selection
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