PKC zeta Polyclonal Antibody
Product Specifications
Background
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.
Abbreviation
PKC ζ
UniProt
Q05513
Host
Rabbit
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.
Target
14-3-3-zetaisoform; AI098070; aPKCzeta; C80388; EC 2.7.11.13; KPCZ; nPKC zeta; nPKC-zeta; OTTHUMP00000001368; OTTHUMP00000044160; PKC 2; PKC ZETA; PKC2; Pkcz; PKCZETA; PKM-zeta; included; PRKCZ; Protein kinase C zeta; Protein kinase C zeta form; Protein kinase C zeta type; r14-3-3; R74924; zetaPKC
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
68kDa
Observed Molecular Weight
80kDa
Citation 01
https://journals.sagepub.com/doi/abs/10.1177/1010428317701442
Isotype
IgG
Available Sizes
Curated Selection
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