NOS3 Polyclonal Antibody
Product Specifications
Background
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) -induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Abbreviation
NOS3
UniProt
P29474
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human NOS3 around the non-phosphorylation site of Ser1177.
Target
CNOS; Constitutive NOS; EC NOS; EC-NOS; ecNOS; Endothelial nitric oxidase synthase; Endothelial nitric oxide synthase; Endothelial nitric oxide synthase 3; Endothelial NOS; eNOS; Nitric oxide synthase 3 (endothelial cell) ; Nitric oxide synthase 3; Nitric oxide synthase 3 endothelial cell; Nitric oxide synthase endothelial; Nitric oxide synthase; endothelial; NOS 3; NOS III; NOS type III; NOS3; NOS3; NOSIII
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
133kDa
Observed Molecular Weight
140kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0009279722002952
Citation 02
https://www.mdpi.com/1587758
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15186546 1 Vial
Lentiviral mouse Wnt10b shRNA (UAS) - Lentiviral mouse Wnt10b shRNA (UAS) (100)
Ask
View Details