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NOS3 Polyclonal Antibody

Product Specifications

Background

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF) -induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Abbreviation

NOS3

UniProt

P29474

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human NOS3 around the non-phosphorylation site of Ser1177.

Target

CNOS; Constitutive NOS; EC NOS; EC-NOS; ecNOS; Endothelial nitric oxidase synthase; Endothelial nitric oxide synthase; Endothelial nitric oxide synthase 3; Endothelial NOS; eNOS; Nitric oxide synthase 3 (endothelial cell) ; Nitric oxide synthase 3; Nitric oxide synthase 3 endothelial cell; Nitric oxide synthase endothelial; Nitric oxide synthase; endothelial; NOS 3; NOS III; NOS type III; NOS3; NOS3; NOSIII

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC-p; IF

Field of Research

Cancer; Cell Biology; Cardiovascular; Metabolism; Neuroscience

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

133kDa

Observed Molecular Weight

140kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0009279722002952

Citation 02

https://www.mdpi.com/1587758

Isotype

IgG

Available Sizes

Frequently Asked Questions

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