MFN2 Polyclonal Antibody
Product Specifications
Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Abbreviation
Mfn2
UniProt
O95140
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human Mfn2.
Target
CMT2A; CMT2A2; CPRP 1; CPRP1; EC 3.6.5.-; Fzo; HSG; hyperplasia suppressor gene; Hypertension related protein 1; KIAA0214; MARF; MFN 2; Mfn2; MFN2; Mitochondrial assembly regulatory factor; Mitofusin-2; Mitofusin2; Transmembrane GTPase MFN2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Cell Biology; Metabolism; Neuroscience; Signal Transduction; Tags and Cell Markers
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/gg4gtd
Product MSDS
https://789.bio/eb/jffrX1
Calculated Molecular Weight
86kDa
Observed Molecular Weight
86kDa
Citation 01
https://cancerci.biomedcentral.com/articles/10.1186/s12935-021-02137-x
Isotype
IgG
Available Sizes
Curated Selection
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