CASP7 Polyclonal Antibody
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.
Abbreviation
Caspase-7
UniProt
P55210
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the N-terminal region of human Caspase-7.
Target
Apoptotic protease Mch-3; Apoptotic protease MCH3; CASP-7; CASP7; CASP7; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase-7 subunit p11; Caspase7; CMH 1; CMH-1; CMH1; ICE LAP3; ICE-LAP3; ICE-like apoptotic protease 3; LICE2; MCH3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; ICC 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34kDa
Observed Molecular Weight
35kDa
Isotype
IgG
Available Sizes
Curated Selection
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