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IL6 Polyclonal Antibody

Product Specifications

Background

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Abbreviation

IL-6

UniProt

P05231

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human IL-6.

Target

Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; B-cell stimulatory factor 2; BSF 2; BSF-2; BSF2; CDF; CTL differentiation factor; Hepatocyte stimulatory factor; HGF; HSF; Hybridoma growth factor; Hybridoma growth factor Interferon beta-2; IFN-beta-2; IFNB2; IL 6; IL-6; IL6; IL6; Interferon beta 2; Interferon beta-2; Interleukin 6; Interleukin 6 (interferon beta 2) ; Interleukin BSF 2; Interleukin-6

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC-p

Field of Research

Cancer; Metabolism; Immunology; Neuroscience

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:100-1:300

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

21-30kDa

Observed Molecular Weight

23kDa

Citation 01

https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12987

Citation 02

https://www.spandidos-publications.com/10.3892/ijmm.2020.4739

Citation 03

https://link.springer.com/article/10.1007/s11655-018-2985-3

Isotype

IgG

Available Sizes

Frequently Asked Questions

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