IL6 Polyclonal Antibody
Product Specifications
Background
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
Abbreviation
IL-6
UniProt
P05231
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human IL-6.
Target
Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; B-cell stimulatory factor 2; BSF 2; BSF-2; BSF2; CDF; CTL differentiation factor; Hepatocyte stimulatory factor; HGF; HSF; Hybridoma growth factor; Hybridoma growth factor Interferon beta-2; IFN-beta-2; IFNB2; IL 6; IL-6; IL6; IL6; Interferon beta 2; Interferon beta-2; Interleukin 6; Interleukin 6 (interferon beta 2) ; Interleukin BSF 2; Interleukin-6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Metabolism; Immunology; Neuroscience
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
21-30kDa
Observed Molecular Weight
23kDa
Citation 01
https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12987
Citation 02
https://www.spandidos-publications.com/10.3892/ijmm.2020.4739
Citation 03
https://link.springer.com/article/10.1007/s11655-018-2985-3
Isotype
IgG
Available Sizes
Curated Selection
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