CBX3 Monoclonal Antibody
Product Specifications
Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.
Abbreviation
CBX3
UniProt
Q13185
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein of HP-1γ
Target
CBX 3; CBX3; CBX3; Chromobox homolog 3 (HP1 gamma homolog; Drosophila) ; Chromobox homolog 3; Chromobox protein homolog 3; GAMMA; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma; HP1 gamma; HP1 gamma homolog; HP1Hs gamma; Modifier 2 protein
Clonality
Monoclonal
Clone
Clone:4F4
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC 1:50-300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
24kDa
Isotype
IgG
Available Sizes
Curated Selection
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