NFKBIB Monoclonal Antibody
Product Specifications
Background
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Abbreviation
IκB β
UniProt
Q15653
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein
Target
I kappa B beta; I-kappa-B-beta; IkappaBbeta; IKB beta; IkB-B; IkB-beta; IKBB; IKBB; IkBbeta; NF kappa BIB; NF-kappa-B inhibitor beta; NF-kappa-BIB; Nfkbib; Thyroid receptor interacting protein 9; Thyroid receptor-interacting protein 9; TR interacting protein 9; TR-interacting protein 9; TRIP-9; TRIP9
Clonality
Monoclonal
Clone
3E4
Conjugation
Unconjugated
Applications
IHC-p
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Immunology; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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