TBP Monoclonal Antibody
Product Specifications
Background
This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
Abbreviation
TBP/TATA Binding Protein
UniProt
P20226
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Protein
Target
GTF2D; GTF2D1; HDL4; SCA17; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; TATA-box-binding protein; TBP; TBP; TFIID; Transcription initiation factor TFIID TBP subunit
Clonality
Monoclonal
Clone
4H2
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/xh80ls
Product MSDS
https://789.bio/eb/KmT4uD
Observed Molecular Weight
35-45kDa
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
