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PI 3 kinase p85 alpha Monoclonal Antibody

Product Specifications

Background

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Abbreviation

PI3 Kinase P85α

UniProt

P27986

Host

Mouse

Reactivity

Mouse; Rat

Immunogen

Recombinant Protein

Target

GRB1; p85 alpha; p85; P85A; Phosphatidylinositol 3 kinase associated p 85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3 kinase; regulatory subunit; polypeptide 1 (p85 alpha) ; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphoinositide 3 kinase; regulatory subunit 1 (alpha) ; PI3 kinase p85 subunit alpha; PI3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K; PI3K regulatory subunit alpha; Pik3r1; PtdIns 3 kinase p85 alpha; PtdIns-3-kinase regulatory subunit alpha; PtdIns-3-kinase regulatory subunit p85-alpha

Clonality

Monoclonal

Clone

3B7

Conjugation

Unconjugated

Applications

WB; IHC-p

Field of Research

Cancer; Metabolism; Immunology; Signal Transduction

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

WB 1:1000-2000; IHC 1:100-200

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Observed Molecular Weight

85kDa

Citation 01

https://www.sciencedirect.com/science/article/pii/S0753332222010769

Isotype

IgG

Available Sizes

Frequently Asked Questions

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