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ATG5 Monoclonal Antibody

Product Specifications

Background

Autophagy protein 5  is a  protein  that in humans is encoded by the  ATG5  gene. It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.

Abbreviation

ATG5

UniProt

Q9H1Y0

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Protein of ATG5

Target

APG 5; APG 5L; APG5; APG5 autophagy 5 like; APG5 like; APG5-like; APG5L; Apoptosis specific protein; Apoptosis-specific protein; ASP; ATG 5; Atg5; ATG5 autophagy related 5 homolog; ATG5; Autophagy protein 5; Autophagy related 5; hAPG5; Homolog of S Cerevisiae autophagy 5; OTTHUMP00000040507

Clonality

Monoclonal

Clone

Clone:5D3

Conjugation

Unconjugated

Applications

WB; IHC-p

Field of Research

Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC 1:50-300

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/vl4pqp

Product MSDS

https://789.bio/eb/n9KOOO

Observed Molecular Weight

55kDa

Citation 01

https://www.spandidos-publications.com/10.3892/or.2021.8241

Isotype

IgG

Available Sizes

Curated Selection

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