AMPK alpha1 Monoclonal Antibody
Product Specifications
Background
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
Abbreviation
AMPK α1
UniProt
Q13131
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide
Target
5 AMP activated protein kinase alpha 1catalytic subunit;5 AMP activated protein kinase catalytic alpha 1 chain;5' AMP activated protein kinase catalytic subunit alpha 1;5'-AMP-activated protein kinase catalytic subunit alpha-1; AAPK1; AAPK1; ACACA kinase; acetyl CoA carboxylase kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase; catalytic; alpha -1; AMPK 1; AMPK alpha 1; AMPK alpha 1 chain; AMPK; AMPK subunit alpha-1; AMPK1; AMPKa1; AMPKalpha1; C130083N04Rik; cb116; EC 2.7.11.1; HMG CoA reductase kinase; HMGCR kinase; hormone sensitive lipase kinase; Hydroxymethylglutaryl CoA reductase kinase; im:7154392; kinase AMPK alpha1; MGC33776; MGC57364; OTTHUMP00000161795; OTTHUMP00000161796; PRKAA 1; PRKAA1; Protein kinase AMP activated alpha 1 catalytic subunit; SNF1-like protein AMPK; SNF1A; Tau protein kinase PRKAA1; wu:fa94c10
Clonality
Monoclonal
Clone
Clone:6B6
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000; IHC 1:50-100
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
63kDa
Isotype
IgG
Available Sizes
Curated Selection
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