PPIB Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Abbreviation
Cyclophilin B
UniProt
P23284
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide
Target
AA408962; AA553318; AI844835; Cphn 2; Cphn2; Cyclophilin B; Cyclophilin like protein; CyP 20b; CYP S1; CYP-S1; CYPB; EC 5.2.1.8; MGC14109; MGC2224; OI9; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B (cyclophilin B) ; Peptidylprolyl isomerase B; PPIase; PPIase B; Ppib; PPIB; Rotamase; Rotamase B; S cyclophilin; S-cyclophilin; SCYLP
Clonality
Monoclonal
Clone
Clone:4D7
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Immunology; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:1000-2000; IHC 1:50-300; IF 1:50-300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Observed Molecular Weight
21kDa
Citation 01
https://pubs.acs.org/doi/abs/10.1021/acschemneuro.2c00208
Isotype
IgG
Available Sizes
Curated Selection
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