ITGA2B Monoclonal Antibody
Product Specifications
Background
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Abbreviation
CD41
UniProt
P08514
Host
Mouse
Reactivity
Human
Immunogen
Synthetic Peptide
Target
Antigen CD41; BDPLT16; BDPLT2; CD41; CD41B; form 2; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; Integrin; alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex; antigen CD41) ; ITA2B; Itga2b; ITGAB; platelet fibrinogen receptor; alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; platelet specific antigen BAK; PPP1R93
Clonality
Monoclonal
Clone
Clone:5D1
Conjugation
Unconjugated
Applications
IHC-p
Field of Research
Cancer; Cardiovascular; Immunology; Signal Transduction; Stem Cells
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
IHC 1:50-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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