CD4 Monoclonal Antibody
Product Specifications
Background
This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Abbreviation
CD4
UniProt
P01730
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide
Target
CD 4; CD4 (L3T4) ; CD4; CD4 antigen (p55) ; CD4 antigen; CD4 molecule; CD4 receptor; CD4+ Lymphocyte deficiency; included; CD4; CD4mut; L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; MGC165891; OTTHUMP00000238897; p55; T cell antigen T4; T cell antigen T4/LEU3; T cell differentiation antigen L3T4; T cell OKT4 deficiency; included; T cell surface antigen T4/Leu 3; T cell surface antigen T4/Leu3; T cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; W3/25; W3/25 antigen
Clonality
Monoclonal
Clone
Clone:9G1
Conjugation
Unconjugated
Applications
IHC-p; IF
Field of Research
Cancer; Immunology; Stem Cells
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
IHC 1:100-1:300; IF 1:50-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://www.sciencedirect.com/science/article/pii/S0889159118304574
Citation 02
https://www.nature.com/articles/s41419-020-02891-2
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items