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CD4 Monoclonal Antibody

Product Specifications

Background

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Abbreviation

CD4

UniProt

P01730

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide

Target

CD 4; CD4 (L3T4) ; CD4; CD4 antigen (p55) ; CD4 antigen; CD4 molecule; CD4 receptor; CD4+ Lymphocyte deficiency; included; CD4; CD4mut; L3T4; Leu3; Ly-4; Lymphocyte antigen CD4; MGC165891; OTTHUMP00000238897; p55; T cell antigen T4; T cell antigen T4/LEU3; T cell differentiation antigen L3T4; T cell OKT4 deficiency; included; T cell surface antigen T4/Leu 3; T cell surface antigen T4/Leu3; T cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; W3/25; W3/25 antigen

Clonality

Monoclonal

Clone

Clone:9G1

Conjugation

Unconjugated

Applications

IHC-p; IF

Field of Research

Cancer; Immunology; Stem Cells

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

IHC 1:100-1:300; IF 1:50-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Citation 01

https://www.sciencedirect.com/science/article/pii/S0889159118304574

Citation 02

https://www.nature.com/articles/s41419-020-02891-2

Isotype

IgG

Available Sizes

Curated Selection

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