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EIF4A1 Monoclonal Antibody

Product Specifications

Background

EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Abbreviation

EIF4A1

UniProt

P60842

Host

Mouse

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide

Target

ATP-dependent RNA helicase eIF4A-1; DDX2; DDX2A; eIF 4A I; eIF-4A-I; EIF4A; eIF4A I; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I; Eukaryotic initiation factor 4AI; eukaryotic translation initiation factor 4A; isoform 1; Eukaryotic translation initiation factor 4A1; IF4A1

Clonality

Monoclonal

Clone

Clone:2B6

Conjugation

Unconjugated

Applications

WB; IHC-p; IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:3000; IHC 1:50-1:300; IF 1:100-1:200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/uqmal8

Product MSDS

https://789.bio/eb/eXLmL8

Observed Molecular Weight

48kDa

Isotype

IgG

Available Sizes

Curated Selection

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