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Histone H3 Monoclonal Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Abbreviation

Histone H3

UniProt

P68431, Q71DI3, P84243

Host

Mouse

Reactivity

Zebrafish

Immunogen

Synthetic Peptide

Target

HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/

Clonality

Monoclonal

Clone

Clone:3C5

Conjugation

Unconjugated

Applications

WB

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

WB 1:1000-3000

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/9zqplp

Product MSDS

https://789.bio/eb/Xf9S8K

Calculated Molecular Weight

15kDa

Observed Molecular Weight

15kDa

Isotype

IgG

Available Sizes

Curated Selection

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