CD16 Monoclonal Antibody
Product Specifications
Background
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Abbreviation
CD16
UniProt
P08637, O75015
Host
Mouse
Reactivity
Human
Immunogen
Synthetic Peptide
Target
CD 16; CD 16a; CD16; CD16a; CD16B; Fc fragment of IgG; Fc fragment of IgG low affinity IIIa receptor (CD16) ; Fc gamma R3; Fc gamma receptor III 2 (CD 16) ; Fc gamma receptor III A; Fc of IgG; Fc-gamma receptor III2 (CD 16) ; Fc-gamma RIII; Fc-gamma RIII-alpha; Fc-gamma RIIIa; FCG 3; FCG3; FCG3A; FC gamma RIIIA; FCGR 3; FCGR 3A; FCGR3; FCGR3A; FCGR3A protein; FCGRIII; FCGRIII-2; FcR 10; FcR-10; FcR10; FcRIII; FcRIIIa; IGFR 3; IGFR3; IgG Fc receptor III 1; IgG Fc receptor III 2; IgG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; immunoglobulin G Fc receptor III-2; Low affinity IIIa receptor; Low affinity immunoglobulin gamma Fc region receptor III A; neutrophil-specific antigen NA
Clonality
Monoclonal
Clone
Clone:2B1
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Immunology; Stem Cells
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28kDa
Observed Molecular Weight
45kDa
Isotype
IgG
Available Sizes
Curated Selection
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