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CD16 Monoclonal Antibody

Product Specifications

Background

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.

Abbreviation

CD16

UniProt

P08637, O75015

Host

Mouse

Reactivity

Human

Immunogen

Synthetic Peptide

Target

CD 16; CD 16a; CD16; CD16a; CD16B; Fc fragment of IgG; Fc fragment of IgG low affinity IIIa receptor (CD16) ; Fc gamma R3; Fc gamma receptor III 2 (CD 16) ; Fc gamma receptor III A; Fc of IgG; Fc-gamma receptor III2 (CD 16) ; Fc-gamma RIII; Fc-gamma RIII-alpha; Fc-gamma RIIIa; FCG 3; FCG3; FCG3A; FC gamma RIIIA; FCGR 3; FCGR 3A; FCGR3; FCGR3A; FCGR3A protein; FCGRIII; FCGRIII-2; FcR 10; FcR-10; FcR10; FcRIII; FcRIIIa; IGFR 3; IGFR3; IgG Fc receptor III 1; IgG Fc receptor III 2; IgG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; immunoglobulin G Fc receptor III-2; Low affinity IIIa receptor; Low affinity immunoglobulin gamma Fc region receptor III A; neutrophil-specific antigen NA

Clonality

Monoclonal

Clone

Clone:2B1

Conjugation

Unconjugated

Applications

WB; IHC-p

Field of Research

Cancer; Immunology; Stem Cells

Purification

Protein A purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-300

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

28kDa

Observed Molecular Weight

45kDa

Isotype

IgG

Available Sizes

Curated Selection

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