CASP9 Monoclonal Antibody
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Abbreviation
Caspase 9
UniProt
P55211
Host
Mouse
Reactivity
Human
Immunogen
Synthetic Peptide
Target
APAF-3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; CASP9; CASP9; Caspase 9 apoptosis related cysteine peptidase; Caspase 9 Dominant Negative; Caspase 9c; Caspase-9; Caspase-9 subunit p10; ICE LAP6; ICE like apoptotic protease 6; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1; regulatory subunit 56; RNCASP9
Clonality
Monoclonal
Clone
Clone:3I3
Conjugation
Unconjugated
Applications
WB; IHC-p; IF; IP
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-300; IF 1:50-1:200; IP 1:100-1:300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46kDa
Observed Molecular Weight
47-51kDa
Citation 01
https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo01547h
Isotype
IgG
Available Sizes
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