CA9 Monoclonal Antibody
Product Specifications
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.
Abbreviation
CA IX
UniProt
Q16790
Host
Mouse
Reactivity
Human
Immunogen
Synthetic Peptide
Target
CA-IX; CA9; CAH9; CAIX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; Carbonic dehydratase; G250; Membrane antigen MN; MN; P54/58N; pMW1; RCC associated protein G250; RCC-associated antigen G250; Renal cell carcinoma-associated antigen G250
Clonality
Monoclonal
Clone
Clone:9B5
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:1000-1:3000; IHC 1:50-300; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50kDa
Observed Molecular Weight
35-38kDa
Isotype
IgG
Available Sizes
Curated Selection
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