AMACR Monoclonal Antibody
Product Specifications
Background
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R) - and (S) -stereoisomers. The conversion to the (S) -stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Abbreviation
AMACR
UniProt
Q9UHK6
Host
Mouse
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide
Target
2 methylacyl CoA racemase;2-methylacyl-CoA racemase; Alpha methylacyl CoA racemase; Alpha-methylacyl-CoA racemase; Amacr; AMACR; AMACRD; CBAS4; EC 5.1.99.4; Macr1; RACE; RM
Clonality
Monoclonal
Clone
Clone:1F1
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cell Biology; Metabolism; Signal Transduction
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:100-1:300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42kDa
Observed Molecular Weight
42kDa
Isotype
IgG
Available Sizes
Curated Selection
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