Histone H3 Monoclonal Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Abbreviation
Histone H3
UniProt
P68431, Q71DI3, P84243
Host
Mouse
Reactivity
Human; Mouse; Rat; Yeast
Immunogen
Recombinant Protein
Target
HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/
Clonality
Monoclonal
Clone
Clone:5B1
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Protein A purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-300; IF 1:100-500; IP 1:100-1:300
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15kDa
Observed Molecular Weight
15kDa
Isotype
IgG
Available Sizes
Frequently Asked Questions
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