Phospho-IRS1 (Tyr896) Polyclonal Antibody
Product Specifications
Background
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Abbreviation
IRS-1 (phospho Tyr896)
UniProt
P35568
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human IRS-1 around the phosphorylation site of Tyr896
Target
HIRS 1; HIRS1; Insulin receptor substrate 1; IRS 1; IRS-1; IRS1; IRS1; OTTHUMP00000164234
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Tags and Cell Markers
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
132kDa
Observed Molecular Weight
180kDa
Isotype
IgG
Available Sizes
Curated Selection
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