Phospho-IRS1 (Tyr896) Polyclonal Antibody

Product Specifications

Background

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

Abbreviation

IRS-1 (phospho Tyr896)

UniProt

P35568

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human IRS-1 around the phosphorylation site of Tyr896

Target

HIRS 1; HIRS1; Insulin receptor substrate 1; IRS 1; IRS-1; IRS1; IRS1; OTTHUMP00000164234

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Tags and Cell Markers

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

132kDa

Observed Molecular Weight

180kDa

Isotype

IgG

Available Sizes

Curated Selection

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