Phospho-Glucocorticoid Receptor (Ser211) Polyclonal Antibody
Product Specifications
Background
Receptor for glucocorticoids (GC) . Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
Abbreviation
GR (phospho Ser211)
UniProt
P04150
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human GR around the phosphorylation site of Ser211
Target
GCCR; GCR; GCR; GCRST; glucocorticoid nuclear receptor variant 1; Glucocorticoid receptor; GR; GRL; Grl1; nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3; group C; member 1 (glucocorticoid receptor)
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
86kDa
Observed Molecular Weight
95kDa
Isotype
IgG
Available Sizes
Curated Selection
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