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Phospho-CREB1 (Ser133) Polyclonal Antibody

Product Specifications

Background

This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.

Abbreviation

CREB-1 (phospho Ser133)

UniProt

P16220

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133

Target

Active transcription factor CREB; cAMP response element binding protein 1; cAMP response element binding protein; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 1; CREB; CREB-1; CREB1; CREB1; Cyclic AMP-responsive element-binding protein 1; MGC9284; OTTHUMP00000163864; OTTHUMP00000163865; OTTHUMP00000206660; OTTHUMP00000206662; OTTHUMP00000206667; Transactivator protein

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC-p; IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling; Immunology

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:100-1:300

Buffer

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

37kDa

Observed Molecular Weight

37kDa

Citation 01

https://www.nature.com/articles/s41598-023-29287-4

Isotype

IgG

Available Sizes

Frequently Asked Questions

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