GP6 Polyclonal Antibody

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11) . Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Glycoprotein 6; Glycoprotein VI; GP6; GPIV; GPVI; GPVI; MGC138168; Platelet collagen receptor; Platelet glycoprotein VI; Platelet glycoprotein VI precursor