GP6 Polyclonal Antibody
Product Specifications
Background
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11) . Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Abbreviation
GP6
UniProt
Q9HCN6
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human GP6
Target
Glycoprotein 6; Glycoprotein VI; GP6; GPIV; GPVI; GPVI; MGC138168; Platelet collagen receptor; Platelet glycoprotein VI; Platelet glycoprotein VI precursor
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cardiovascular
Purification
Antigen affinity purification
Concentration
1.14 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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