GBA Polyclonal Antibody
Product Specifications
Background
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Abbreviation
GBA
UniProt
P04062
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human GBA
Target
Acid beta glucosidase; Acid beta-glucosidase; Alglucerase; Beta glucocerebrosidase; BETA GLUCOSIDASE; ACID; Beta-glucocerebrosidase; betaGC; D glucosyl N acylsphingosine glucohydrolase; D-glucosyl-N-acylsphingosine glucohydrolase; EC 3.2.1.45 ; GBA; Gba protein ; GBA1; GC; GCase; GCB; GLCM; GLUC; Glucocerebrosidase (alt.) ; Glucocerebrosidase; GLUCOCEREBROSIDASE PSEUDOGENE; Glucosidase beta; Glucosidase; beta; acid; Glucosidase; beta; acid (includes glucosylceramidase) ; Glucosylceramidase; Imiglucerase; Lysosomal glucocerebrosidase ; OTTHUMP00000033992; OTTHUMP00000033993
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Metabolism; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
1.56 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
60 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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