ACOD1 Polyclonal Antibody
Product Specifications
Background
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs) -mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Abbreviation
ACOD1
UniProt
A6NK06
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human ACOD1
Target
ACOD1; Aconitate decarboxylase 1; Aconitate decarboxylase; CAD; Cis aconitate decarboxylase; Immune responsive gene 1 protein homolog; Immune-responsive gene 1 protein homolog; Immunoresponsive 1 homolog (mouse) ; Irg1; IRG1; OC116; OPTB1; TCTIRC7
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Metabolism; Immunology; Signal transduction
Purification
Antigen affinity purification
Concentration
1.32 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
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