ACOD1 Polyclonal Antibody
Product Specifications
Background
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs) -mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Abbreviation
ACOD1
UniProt
A6NK06
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human ACOD1
Target
ACOD1; Aconitate decarboxylase 1; Aconitate decarboxylase; CAD; Cis aconitate decarboxylase; Immune responsive gene 1 protein homolog; Immune-responsive gene 1 protein homolog; Immunoresponsive 1 homolog (mouse) ; Irg1; IRG1; OC116; OPTB1; TCTIRC7
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Metabolism; Immunology; Signal transduction
Purification
Antigen affinity purification
Concentration
1.32 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
