MECOM Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Abbreviation
MECOM
UniProt
Q03112
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human MECOM
Target
Ecotropic Virus Integration Site 1 Protein Homolog; MDS1 And EVI1 Complex Locus Protein; PR Domain 3; EVI1; MDS1; MDS1 And EVI1 Complex Locus Protein EVI1; MDS1 And EVI1 Complex Locus Protein MDS1; Ecotropic Viral Integration Site 1; Myelodysplasia Syndrome 1 Protein; Zinc Finger Protein Evi1; Oncogene EVI1; AML1-EVI-1; MDS1-EVI1; RUSAT2; KMT8E; PRDM3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
1.68 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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