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EBF2 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.

Abbreviation

EBF2

UniProt

Q9HAK2

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human EBF2

Target

COE 2; COE2; COE2; Collier Olf and EBF 2; Early B cell factor 2; Early B-cell factor 2; EBF 2; EBF-2; Ebf2; FLJ11500; Metencephalon mesencephalnon olfactory transcription factor 1; O/E 3; O/E3; OE 3; OE3; OLF 1/EBF like 3; Transcription factor COE2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling; Neuroscience

Purification

Antigen affinity purification

Concentration

1.68 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

63 kDa

Observed Molecular Weight

Refer to figures

Isotype

IgG

Available Sizes

Frequently Asked Questions

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