PNPO Polyclonal Antibody
Product Specifications
Background
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Abbreviation
PNPO
UniProt
Q9NVS9
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human PNPO
Target
EC 1.4.3.5; FLJ10535; PDXPO; PNPO; PNPO; Pyridoxal 5' phosphate synthase; pyridoxamine 5' phosphate oxidase; Pyridoxamine phosphate oxidase ; Pyridoxamine-phosphate oxidase; pyridoxine 5' phosphate oxidase; Pyridoxine-5'-phosphate oxidase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Metabolism; Neuroscience; Signal transduction
Purification
Antigen affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:20-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
30 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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