IBA57 Polyclonal Antibody

The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

C1orf69; CAF17; Chromosome 1 open reading frame 69; FLJ12734; FLJ13849; IBA57; IBA57 homolog iron sulfur cluster assembly; IBA57 iron sulfur cluster assembly homolog ; IBA57 iron sulfur cluster assembly homolog (S. cerevisiae) ; IBA57; S. cerevisiae; homolog of; Iron sulfur cluster assembly factor for biotin synthase and aconitase like ; iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins; with a mass of 57kDa; Iron-sulfur cluster assembly factor homolog; Mitochondrial proteins with a mass of 57kDa; MMDS3; Putative transferase C1orf69 mitochondrial; Putative transferase CAF17; mitochondrial; SPG74