HUWE1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related) ) . This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Abbreviation
HUWE1
UniProt
Q7Z6Z7
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human HUWE1
Target
ARF binding protein 1; ARF BP1; ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin protein ligase HUWE1; E3 ubiquitin-protein ligase HUWE1; HECT; HECT domain protein LASU1; HECT UBA and WWE domain containing protein 1; HectH9; Homologous to E6AP carboxyl terminus homologous protein 9; Huwe1; HUWE1; Ib772; Large structure of UREB1; LASU1; Mcl 1 ubiquitin ligase E3; Mcl-1 ubiquitin ligase E3; Mule; UBA and WWE domain-containing protein 1; Upstream regulatory element-binding protein 1; URE-B1; URE-binding protein 1; UREB1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology
Purification
Antigen affinity purification
Concentration
0.8 mg/mL
Dilution
IHC 1:10-1:50
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/qqww50
Product MSDS
https://789.bio/eb/LKiXLC
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
