GKN1 Polyclonal Antibody
Product Specifications
Background
Gastrokine 1 (GKN1), a stomach-specic protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.
Abbreviation
GKN1
UniProt
Q9NS71
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human GKN1
Target
18 kDa antrum mucosa protein; AMP 18; AMP-18; AMP18; Antrum mucosa protein;18-KD; BRICD 1; BRICD1; BRICHOS domain containing 1; CA 11; CA11; CA11 gene; CA11 protein; FOV; Foveolin; Gastrokine-1; Gastrokine1; GKN 1; Gkn1; GKN1; MGC70354; Protein CA11; UNQ489/PRO1005
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Tags and Cell Markers
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG
Available Sizes
Curated Selection
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