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HOXD8 Polyclonal Antibody

Product Specifications

Background

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.

Abbreviation

HOXD8

UniProt

P13378

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Synthetic peptide of human HOXD8

Target

Homeo Box D8; HOX4E; Homeobox Protein 5.4; Homeo Box 4E; HOX5.4; HOX4

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology

Purification

Antigen affinity purification

Concentration

1.6 mg/mL

Dilution

IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Product Datasheet

https://789.bio/ea/v9h1td

Product MSDS

https://789.bio/eb/j9Oi98

Isotype

IgG

Available Sizes

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