WNK4 Polyclonal Antibody

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K (+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

PHA 2B; PHA2B; PRKWNK 4; PRKWNK4; Protein kinase lysine deficient 4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4; Serine/threonine protein kinase WNK4; Serine/threonine-protein kinase WNK4; WNK lysine deficient protein kinase 4; Wnk4; WNK4