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WEE1 Polyclonal Antibody

Product Specifications

Background

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.WEE1 (WEE1 G2 Checkpoint Kinase) is a Protein Coding gene. Among its related pathways are PLK1 signaling events and Cell cycle Role of 14-3-3 proteins in cell cycle regulation. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is WEE2.

Abbreviation

WEE1

UniProt

P30291

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human WEE1

Target

DKFZp686I18166; EC 2.7.10.2; FLJ16446; MGC105683; OTTHUMP00000231338; OTTHUMP00000231339; Wee 1; WEE 1 homolog 1 (S. pombe) ; WEE1; WEE1 homolog (S. pombe) ; Wee1 homolog; WEE1 homolog S. pombe; Wee1 like protein kinase; Wee1 tyrosine kinase; Wee1+ homolog; Wee1+ S. pombe homolog; WEE1; S. pombe; homolog of; WEE1; somatic; Wee1-like protein kinase; WEE1; WEE1A; Wee1A kinase; WEE1hu

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

1.3 mg/mL

Dilution

IHC 1:30-1:150

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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