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NRG2 Polyclonal Antibody

Product Specifications

Background

This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Abbreviation

NRG2

UniProt

O14511

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide of human NRG2

Target

Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2; NTAK; Pro NRG2; Pro-NRG2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Neuroscience; Signal Transduction

Purification

Antigen affinity purification

Concentration

1 mg/mL

Dilution

IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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